About the workshop
This workshop provides a deep dive into Pumas, a powerful pharmacometric platform designed for modeling and simulation in drug development. Over two days, participants will gain hands-on experience and knowledge, starting from basic workflows to advanced topics such as population pharmacokinetics (PK), bioequivalence, and sequential PKPD modeling. Experts will guide attendees through various stages of model building, diagnostics, and data wrangling, with opportunities to explore specialized areas like absorption models, using non-Gaussian random effects and data models, and time-to-event analysis.
The workshop will cover
- Non-Compartmental Analysis in PumasCP
- Population pharmacokinetics Modeling and Simulation in Pumas
- Simulations for decision-making in patient care and drug development
Target audience
Postgraduate students of pharmacy or medicine disciplines, academics, scientists, pharmacists, medical doctors and other allied health professionals
Maximum number of participants: 40
Venue: Bilik Seminar 4, HSAAS UPM
Speakers
- Sharath Kumar HJ | PumasAI (Scientist)
- Saugandhika Minnikanti, PhD | PumasAI (Scientist)
Tentative Schedule (Day 1) – Introduction to PumasCP and Julia:
Time | Activity |
|---|---|
09:00 – 09:30 | Welcome C Environment Setup |
09:30 – 10:30 | Introduction: NCA and PumasCP |
10:30 – 10:45 | Morning Break |
10:45 – 11:45 | NCA using PumasCP |
11:45 – 12:30 | Dose Proportionality and Superposition using PumasCP |
12:30 – 13:30 | Lunch Break |
13:30 – 14:30 | Food effect, Drug-Drug interaction, and Urine analysis in PumasCP |
14:30 – 14:45 | Afternoon Break |
14:45 – 15:30 | Introduction to Julia |
15:30 – 16:30 | Data Wrangling and Visualization in Julia |
Tentative Schedule (Day 2) – Introduction to Pumas and PopPK modeling workflows:
Time | Activity |
|---|---|
09:00 – 09:30 | Introduction to Pumas |
09:30 – 10:30 | PopPK analysis in Pumas – Part 1 (Data representation, Model representation, Parameter estimation) |
10:30 – 10:45 | Morning Break |
10:45 – 12:30 | PopPK analysis in Pumas – Part 2 (Model Diagnostics and Evaluation) |
12:30 – 13:30 | Lunch Break |
13:30 – 14:30 | Covariate analysis |
14:30 – 14:45 | Afternoon Break |
14:45 – 15:45 | PopPK Simulations |
15:45 – 16:30 | NCA in Pumas |
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