Prof. Dr Karolien De Bosscher
Nuclear Receptor Signalling
Ghent University, Belgium
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Professor Dr Karolien De Bosscher, a molecular biologist, earned her Ph.D. from UGent in 2000. Following postdoctoral research at Cancer Research UK with an EMBO fellowship she returned to Belgium to conduct nuclear receptor research as a postdoctoral fellow of FWO-Vlaanderen. In 2013, she secured a research professorship, combining research and teaching at UGent. From 2019 onwards, she is a full professor at UGent and principal investigator at the VIB Center for Medical Biotechnology.
Throughout her career, Dr. De Bosscher focused on unraveling nuclear receptor intricacies, exploring anti-inflammatory and anti-cancer mechanisms. Her team investigates selective glucocorticoid receptor modulation, metabolic actions of nuclear receptors, and crosstalk mechanisms in hematological cancers. Dr. De Bosscher’s lab decodes how nuclear receptors transduce signals, aiming to innovate receptor-targeting strategies for enhanced therapeutic benefits. The team develops cell-based tools to capture nuclear receptors’ complexity, contributing to drug discovery platforms.
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